BIOCOMPATIBLE PERFORATED MEMBRANES, PROCESS FOR THEIR PREPARATION , THEIR USE AS A SUPPORT IN THE IN VITRO GROWTH OF EPITHELIAL CELLS, THE ARTIFICIAL SKIN OBTAINED IN THIS MANNER, AND ITS USE IN SKIN GRAFTS

摘要

The invention relates to biocompatible membranes constructed of materials of natural, synthetic or semisynthetic origin, and having a thickness of between 10 and 500 mu , characterised by containing an ordered series of holes of a constant size between 10 and 1000 mu , separated from each other by a constant distance of between 50 and 1000 mu , and obtained by perforation by mechanical, thermal laser or ultraviolet radiation means, they being suitable for use as a support for the in vitro growth of epithelial cells, the invention also relating to the artificial skin obtained thereby and its use in grafts.