HUMAN MONOCLONAL ANTIBODIES AGAINST RABIES VIRUSES, THE PRODUCTION AND THE USE THEREOF

摘要

BEHRINGWERKE AKTIENGESELLSCHAFT HOE 90/B 010 - Ma 809 Dr. Lp/rd Human monoclonal antibodies against rabies viruses, the production and the use thereof The present patent application relates to human monoclonal antibodies against rabies viruses, and the use thereof in diagnosis, prevention and therapy. Antibodies against the epitope, defined by the human monoclonal antibody TW-1, on the 67 kD glycoprotein of the virus envelope gives a better protection against the outbreak of rabies, after infection has taken place, than commercial preparations of human immunoglobulins.