| 摘要 |
A diaryl sulphide derivative of the formula <IMAGE> (I) in which R1 represents a thiazolamino radical of the formulae <IMAGE> +TR <IMAGE> wherein R5 represents hydrogen, alkyl, aralkyl or acyl, R6 and R6' are identical or different and represent hydrogen, alkyl, aralkyl or aryl, R7 represents alkyl, cycloalkyl, aralkyl, acyl or aryl and n represents the number 1 or 2, R2 and R3 are identical or different and represent hydrogen, alkyl, alkenyl, cycloalkyl, alkoxy, alkylthio, halogenoalkyl, halogenoalkoxy, halogenoalkylthio, aryl, aralkyl, aryloxy, aralkoxy, aralkylthio, acyl, carboxyl, alkoxycarbonyl, carboxyalkyl, alkoxycarbonylalkyl, nitro, cyano or halogen, or represent a group of the formula <IMAGE> wherein R8 and R9 are identical or different and represent hydrogen, alkyl, aryl, aralkyl, acyl, trifluoroacetyl, alkylsulphonyl, arylsulphonyl, trifluoromethylphenylsulphonyl or tolylsulphonyl and R4 has one of the abovementioned meanings or R1, or represents hydrogen, alkyl, alkenyl, cycloalkyl, alkoxy, alkylthio, halogenoalkyl, halogenoalkoxy, halogenoalkylthio, aryl, aralkyl, aryloxy, aralkoxy, aralkylthio, acyl, carboxyl, alkoxycarbonyl, carboxyalkyl, alkoxycarbonylalkyl, nitro, cyano or halogen, or represents a group of the formula <IMAGE> wherein R8 and R9 have the abovementioned meanings, and salts thereof. Such diaryl sulphide derivatives being useful as active compounds in the treatment and prevention of diseases of the respiratory tract and cardiovascular diseases.
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