发明名称 LIPOSOME FORMING AGENT
摘要 PURPOSE:To enhance the safety and stability of the title agent by preparing the liposome forming agent from the 2-[(2-hydroxy-N-acyl)acyloxypropyl amino]ethyl phosphoric ester shown by a specified formula. CONSTITUTION:The liposome forming agent is prepared from the 2-[(2-hydroxy- N-acyl)acyloxypropylamino]ethyl phosphoric ester expressed by formula I (R is 8-20 C straight-chain or branched-chain alkyls, M shows a sodium ion, a potassium ion, an ammonium ion, and a triethanolamine ion). Ultrasonic treatment, an injection method and surfactant treatment can be applied to form the liposome forming agent. In addition, the liposome forming agent is compatible with the organisms and is the substance having high safety.
申请公布号 JPS63185441(A) 申请公布日期 1988.08.01
申请号 JP19870016371 申请日期 1987.01.27
申请人 KANEBO LTD 发明人 TSUBONE KAZUYUKI
分类号 A61K47/26;A61K8/11;A61K8/14;A61K8/41;A61K8/55;A61K9/10;A61K9/127;A61Q19/00;B01J13/02;C07F9/10 主分类号 A61K47/26
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