PROTEOLYTIC COVER OF WOUNDS

摘要

The invention pertains to a cover for a wound which can be in the form of a powder or a dry powdery fluid and serves for covering and treatment of ulcerous and necrotic wounds. It may consist of animal or fungous chitin or chitosan in a powdered form of particle size 0.01 to 0.3 mm or of crosslinked dextran in the form of spheric particles of diameter 0.05 to 0.5 mm and of an immobilized protease. The enzymes are chemically bonded to the structure of the biopolymeric carrier and provide cleaning of the wound by dissolution of undesirable protein material, in particular fibrin, necrotic tissues, components of pus, and the like. Additionally, the adsorption and regeneration effects of the powder facilitates the suction of exudate and purulent matter infected with bacteria into an interstitial capillary space and the material of particles. The cover according to the invention acts by fast cleaning of necrotic defects and speeds up the granulation and healing of wound. The invention can be utilized in pharmaceutical production.