1,5-Benzoxathiepin derivatives, their production and use.

摘要

Compounds of the formula: <CHEM> wherein R is hydroxy or lower alkoxy and X is lower alkoxycarbonyl, and their salts possess serotonin S2 receptor blocking activity, calcium antagonism, actions to relieve cerebral vasospasm and to improve renal circulation, and diuretic and antithrombotic activities, and are useful as prophylactic and therapeutic agents for ischemic cardiopathies, thrombosis, hypertension and cerebral circulatory disorders.