| 发明名称 |
Regiospecific synthesis of anthracyclinone compounds such as daunomycinone |
| 摘要 |
A regiospecific synthesis for anthracyclinones asymmetric is disclosed. The synthesis is based upon a regiospecific bromination of the C-7 position of the alpha -tetralone which after transposing the keto group to the beta -position and reaction with an organo-lithium compound is condensed with a phthalate ester.
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| 申请公布号 |
US4374979(A) |
申请公布日期 |
1983.02.22 |
| 申请号 |
US19810258193 |
申请日期 |
1981.04.27 |
| 申请人 |
THE UNIVERSITY OF KANSAS ENDOWMENT ASSOCIATION |
发明人 |
MITSCHER, LESTER A. |
| 分类号 |
C07C43/225;C07C43/23;C07C45/46;C07C45/58;C07C45/59;C07C45/63;C07C205/57;C07D303/22;(IPC1-7):C07H15/24;C07C49/72;C07C49/74;C07C49/84 |
主分类号 |
C07C43/225 |
| 代理机构 |
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代理人 |
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