发明名称 |
PROCESS FOR PRODUCING NEW PYRIDO-SQUARE BRACKET-2,3,B-SQUARE BRACKET CLOSED-SQUARE BRACKET-1,5-SQUARE BRACKET CLOSED-BENZODLASEPIN-5-ONE DERIVATIVES |
摘要 |
Compounds of the formula <IMAGE> wherein R1-is hydrogen, alkyl of 1 to 6 carbon atoms or benzyl; R2-is alkyl of 1 to 6 carbon atoms, cycloalkyl of 5 to 7 carbon atoms or, together with R1 and the adjacent nitrogen atom, pyrrolidino, piperidino, hexamethyleneimino, morpholino or N'-methyl-piperazino, where each of the heterocycles may have one or two alkyl of 1 to 3 carbon atoms or one or two methoxy substituents attached thereto; R3,-R4 and R5 are each hydrogen or methyl; R6-is alkyl of 1 to 4 carbon atoms; and A-is alkylene of 2 to 4 carbon atoms; AND NON-TOXIC, PHARMACOLOGICALLY ACCEPTABLE ACID ADDITION SALTS THEREOF; THE COMPOUNDS AS WELL AS THEIR SALTS ARE USEFUL AS BRONCHOSPASMOLYTICS AND BRONCHOSECRETOLYTICS. |
申请公布号 |
HU179802(B) |
申请公布日期 |
1982.12.28 |
申请号 |
HU1977TO01063 |
申请日期 |
1977.09.28 |
申请人 |
THOMAE GMBH DR KARL |
发明人 |
SCHMIDT,GUENTHER,DE;PUESCHMANN,SIGFRID,DE;ENGELHARDT,GUENTHER,DE |
分类号 |
A61K31/55;A61K31/551;A61P11/08;A61P11/10;C07D213/80;C07D471/04;(IPC1-7):07D471/04 |
主分类号 |
A61K31/55 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|