发明名称 PHENYLGYCINE DERIVATIVES,PHARMACEUTICAL COMPOSITIONS AND METHOD OF USE
摘要 Derivates of L- and DL-hydroxyphenylglycines of the formula <IMAGE> (II) and the pharmaceutically acceptable salts thereof, wherein R is hydrogen or methyl, R1 is hydrogen, amino or alkoxy having from one to six carbon atoms and R2 is the residue of certain alpha -amino acids are useful in treating diseases and conditions which are characterized by reduced blood flow, oxygen availability or carbohydrate metabolism in the cardiovascular system. Derivatives of D-hydroxyphenylglycine of formula (II) are substantially inactive in treating such diseases and conditions.
申请公布号 PH14064(A) 申请公布日期 1981.01.26
申请号 PH19150000210 申请日期 1978.04.17
申请人 PFIZER CORP 发明人 BARNISH I;DANILEWICZ J;CROSS P
分类号 A61K38/00;A61P3/08;C07K5/06;C07K5/065 主分类号 A61K38/00
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