| 摘要 |
Cephem derivs.(I, R1 = H, alkyl, aryl, aralkyl, heterocyclic radical; R2 = H; R3 = H, acetyloxy, azido, alkyloxy, cyano, aryloxy, aralkyloxy, heterocyclic thio; M2 = M1 or H; M3 = alkali metal, t-organic cation, H) were prepd. by reaction of II (M1 = organic or inorganic cation) and III in aq. soln. Thus, 2.1 g monolithium phenylmalinate and 2.14 g 7-amino-3-methyl-3-cephem-4-carboxylic acid were reacted in aq. DMF SO3 soln. at 0-5≦̸C, pH 7.5-8.0 for 30 min to give I.
|
