发明名称 Polyflavone cardiovascular agents - by extracting vegetable matter with methanol and pptn. with methylene chloride or ethyl acetate
摘要 <p>Medicaments contg. as active ingredient, a polyflavanic vegetable extract, having a mol. wt. between 2000-3000 and giving cyanidine when hydrolysed under acid conditions in an inert atmosphere, are new. Addition complexes of the extract with bases and nitrogen cpds. may also be used. Pref. extracts contain a hexameric to nonameric polyflavone derived from a heptahydroxy flavone. In an example, 1 kg powdered Poterium spinosum roots are extracted with methanol, concentrated and precipitated with methylene chloride. After a supplementary purification the yield was 9.5% on starting material. Treatment of cardiovascular disorders, infraction, arhythmia, atheroma, anoxia, senescence, diabetes. They are also radio protection agents.</p>
申请公布号 FR2338048(A2) 申请公布日期 1977.08.12
申请号 FR19760001069 申请日期 1976.01.16
申请人 FABRE PIERRE SA 发明人 RENE BELLE ET PHILIPPE HATINGUAIS;HATINGUAIS PHILIPPE
分类号 A61K31/35;A61K36/185;A61K36/58;A61K36/73;C07D311/40;(IPC1-7):61K35/78;07G17/00 主分类号 A61K31/35
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