发明名称 |
Diagnostic and Therapeutic Use of a Novel Growth Factor, Neublasmin |
摘要 |
The present invention relates to the field of diagnostic and therapeutic use of proteins and genes, in particular to the diagnostic and therapeutic use of a secreted human hormone/growth factor, Neublasmin, and use or the gene coding for Neublasmin in the diagnosis and treatment of testicular disorders, in particular diagnosis and treatment of germ cell tumours and infertility. The invention also relates to use of Neublasmin in the treatment of CNS disorders. Neublasmin is expressed at high levels in human adult testicles and in developing mouse testicles from pn 22 and onwards. Expression or Neublasmin is strongly up-regulated in carcinoma in situ. Expression is also seen in foetal and adult brain.
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申请公布号 |
US2008318853(A1) |
申请公布日期 |
2008.12.25 |
申请号 |
US20050666949 |
申请日期 |
2005.11.04 |
申请人 |
NSGENE A/S |
发明人 |
GRONBORG METTE;BLOM NIKOLAJ |
分类号 |
C07K14/475;A61K38/17;C07K1/04;C07K16/22;C12N5/06;C12N15/12;C12P21/02;C12Q1/68;G01N33/53;G01N33/554;G01N33/68 |
主分类号 |
C07K14/475 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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