摘要 |
PROBLEM TO BE SOLVED: To provide a method for producing a quazepam crystal useful as a medicine. SOLUTION: Quazepam crystal satisfying a melting point specification of a quazepam technical product of 146-151°C is obtained by adding quazepam (chemical name: 7-chloro-5-(2-fluorophenyl)-1,3-dihydro-1-(2,2,2-trifluoroethyl)-2H-1,4-benzodiazepine-2-thione) to ethanol or toluene solvent, dissolving the quazepam in the solvent by heating and then cooling the resultant quazepam solution. COPYRIGHT: (C)2007,JPO&INPIT
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