| 发明名称 |
COMPOUND AND METHOD FOR LOWERING CHOLESTEROL LEVEL WITHOUT INDUCING HYPERTRIGLYCERIDEMIA |
| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a method for lowering cholesterol level, delaying the onset of atherosclerosis or treating atherosclerosis in a mammal without inducing hypertriglyceridemia. <P>SOLUTION: Total serum cholesterol level can be lowered without inducing hypertriglyceridemia by a method involving the administration of an apoE polypeptide or nucleic acid to a mammal, or expressing these compounds in a mammal. <P>COPYRIGHT: (C)2009,JPO&INPIT |
| 申请公布号 |
JP2009171980(A) |
申请公布日期 |
2009.08.06 |
| 申请号 |
JP20090069530 |
申请日期 |
2009.03.23 |
| 申请人 |
KOS PHARMACEUTICALS INC;TRUSTEES OF BOSTON UNIV |
发明人 |
ZANNIS VASSILIS I;KYPREOS KYRIAKOS E |
| 分类号 |
C12N15/09;A61K9/127;A61K35/76;A61K38/00;A61K47/42;A61K47/48;A61K48/00;A61P3/06;A61P9/10;C07K14/775;C12N5/08 |
主分类号 |
C12N15/09 |
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