Nonlinear peptides hydropathycally complementary to known amino acid sequences, process for the production and uses thereof.

摘要

This invention relates to nonlinear peptides which are hydropathically complementary to known amino acid sequences and are covalently linked to an amino acid nucleus. Such molecules are employed both for affinity chromatography applications and for analytical procedures for determining peptide analytes in complex matrices. More particularly, peptides complementary to endothelin fragments are employed for the identification of proteolytic activities or of activities that inhibit proteolytic activities.