| 摘要 |
<p>NEW MATERIAL:A compound expressed by formula I [R<1> represents silyl which is a protecting group of OH; * denotes asymmetric center and represents stereoisomers of (1S, 4R), (1R, 4S) derived therefrom or a mixture thereof]. EXAMPLE:4-tert-Butyldimethylsilyloxy-3-chloro-2-cyclopenten-1-ol. USE:An intermediate for synthesis of punaglandin having carcinostatic and antiviral action. PREPARATION:An ester expressed by formula II (example; 3-acetoxy-5-tert- butyldimethylsilyloxy-1-chlorocyclopentene) is hydrolyzed in the presence of an enzyme (example; liver esterase).</p> |
