发明名称 |
Compositions comprising methanediphosphonic acids and ion-exchangers. |
摘要 |
The invention relates to a novel advantageous oral administration form for methanediphosphonates, in particular the active substance disodium pamidronate. A preferred administration form contains: a) disodium 3-amino-1-hydroxypropane-1,1-diphosphonate (disodium pamidronate); b) cationic ion exchange resin based on a styrene/divinylbenzene copolymer with an exchangeable aminophosphonate group and, where appropriate c) further pharmaceutically acceptable ancillary substances. The ingredients can be processed to tablets, coated tablets, capsules etc.
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申请公布号 |
EP0566535(A1) |
申请公布日期 |
1993.10.20 |
申请号 |
EP19930810246 |
申请日期 |
1993.04.06 |
申请人 |
CIBA-GEIGY AG |
发明人 |
KHANNA, SATISH CHANDRA, DR.;GREEN, JONATHAN, DR. |
分类号 |
A61K9/20;A61K9/28;A61K9/48;A61K31/66;A61K31/675;A61K47/48;A61P3/00;A61P3/14;C07F9/38;(IPC1-7):A61K31/66 |
主分类号 |
A61K9/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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