发明名称 Compositions comprising methanediphosphonic acids and ion-exchangers.
摘要 The invention relates to a novel advantageous oral administration form for methanediphosphonates, in particular the active substance disodium pamidronate. A preferred administration form contains: a) disodium 3-amino-1-hydroxypropane-1,1-diphosphonate (disodium pamidronate); b) cationic ion exchange resin based on a styrene/divinylbenzene copolymer with an exchangeable aminophosphonate group and, where appropriate c) further pharmaceutically acceptable ancillary substances. The ingredients can be processed to tablets, coated tablets, capsules etc.
申请公布号 EP0566535(A1) 申请公布日期 1993.10.20
申请号 EP19930810246 申请日期 1993.04.06
申请人 CIBA-GEIGY AG 发明人 KHANNA, SATISH CHANDRA, DR.;GREEN, JONATHAN, DR.
分类号 A61K9/20;A61K9/28;A61K9/48;A61K31/66;A61K31/675;A61K47/48;A61P3/00;A61P3/14;C07F9/38;(IPC1-7):A61K31/66 主分类号 A61K9/20
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