发明名称 Cyclopropyl fused thiazin-2-amine compounds as beta-secretase inhibitors and methods of use
摘要 The present invention provides a new class of compounds useful for the modulation of beta-secretase enzyme (BACE) activity. The compounds have a general Formula (I): wherein variables A
申请公布号 AU2015301028(A1) 申请公布日期 2017.03.09
申请号 AU20150301028 申请日期 2015.08.05
申请人 Amgen Inc. 发明人 Allen, Jennifer R.;Amegadzie, Albert;Bourbeau, Matthew P.;Brown, James A.;Chen, Jian J.;Cheng, Yuan;Frohn, Michael J.;Guzman-Perez, Angel;Harrington, Paul E.;Liu, Longbin;Liu, Qingyian;Low, Jonathan D.;Ma, Vu Van;Manning, James;Minatti, Ana Elena;Nguyen, Thomas T.;Nishmura, Nobuko;Norman, Mark H.;Pettus, Liping H.;Pickrell, Alexander J.;Qian, Wenyuan;Rumfelt, Shannon;Rzasa, Robert M.;Siegmund, Aaron C.;Stec, Markian M.;White, Ryan;Xue, Qiufen
分类号 C07D417/04;A61K31/5415;A61P25/28;C07D279/08;C07D417/14;C07D471/04 主分类号 C07D417/04
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