发明名称 |
STABLE TABLET CONTAINING 4,5-EPOXYMORPHINAN DERIVATIVE |
摘要 |
The present invention relates to a stable tablet comprising a 4,5-epoxymorphinan derivative or a pharmacologically acceptable acid addition salt thereof as an effective ingredient. That is, the tablet according to the present invention comprises: (1) as the effective ingredient, a specific 4,5-epoxymorphinan derivative or a pharmacologically acceptable acid addition salt; (2) sodium thiosulfate; (3) at least one selected from the group consisting of saccharides and sugar alcohols; and (4) crospovidone, sodium carboxymethyl starch or a mixture thereof, in which tablet the content of the aforementioned (4) is 1 to 20% by weight per unit weight containing the aforementioned effective ingredient. |
申请公布号 |
CA2740476(C) |
申请公布日期 |
2016.04.05 |
申请号 |
CA20092740476 |
申请日期 |
2009.10.23 |
申请人 |
TORAY INDUSTRIES, INC. |
发明人 |
OHTA, KOTOE;TAKAKI, SUGURU;HORIUCHI, YASUHIDE |
分类号 |
A61K31/485;A61K9/20;A61K9/28;A61K47/02;A61K47/26;A61K47/32;A61K47/36;A61P17/04 |
主分类号 |
A61K31/485 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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