发明名称 |
O-GLCNAC TRANSFERASE (OGT) INHIBITORS AND USES THEREOF |
摘要 |
The present invention provides inhibitors of O-GlcNAc transferase. Typically, the inhibitors are quinolinone-6-sulfonamides. The invention also provides pharmaceutical compositions thereof and methods for using the same in diabetes and complications thereof, metabolic diseases, neurodegenerative diseases, proliferative diseases (e.g., cancers), autoimmune diseases, and inflammatory diseases. |
申请公布号 |
WO2016004180(A1) |
申请公布日期 |
2016.01.07 |
申请号 |
WO2015US38792 |
申请日期 |
2015.07.01 |
申请人 |
PRESIDENT AND FELLOWS OF HARVARD COLLEGE |
发明人 |
KAHNE, SUZANNE, WALKER;ORTIZ MEOZ, RODRIGO, FERMIN |
分类号 |
A61K31/4709;A61K31/517;C07D239/96;C07D405/12 |
主分类号 |
A61K31/4709 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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