| 发明名称 |
Oncolytic adenovirus compositions |
| 摘要 |
<p>Provided herein is an adenovirus comprising an E1A polypeptide comprising one or more modifications and comprising an E4orf6/7 polypeptide comprising one or more modifications. Compositions and kits comprising the modified adenoviruses are also provided. Further, provided is a method of treating a proliferative disorder in a subject comprising administering to the subject an adenovirus comprising the E1A polypeptide comprising one or more modifications and comprising the E4orf6/7 polypeptide comprising one or more modifications.</p> |
| 申请公布号 |
AU2014236207(A1) |
申请公布日期 |
2015.09.17 |
| 申请号 |
AU20140236207 |
申请日期 |
2014.03.14 |
| 申请人 |
SALK INSTITUTE FOR BIOLOGICAL STUDIES |
发明人 |
O'SHEA, CLODAGH;MIYAKE-STONER, SHIGEKI |
| 分类号 |
C12N15/861 |
主分类号 |
C12N15/861 |
| 代理机构 |
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代理人 |
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