Anti-TNF alpha producing lactic acid bacteria for the treatment of chronic enterocolitis

摘要

Treatments for chronic enterocolitis are disclosed. More specifically, methods for administration of pharmaceutical compositions that include anti-TNF-alpha antibody producing lactic acid microorganisms, such as Lactobacillus sp. and Saccharomyces sp., are disclosed for the treatment of chronic enterocolitis.

主权项

1. A method of treating inflammatory bowel disease (IBD) by orally administering a therapeutically effective amount of an anti-TNFα VHH producing Lactococcus lactis to an individual in need thereof, wherein said anti-TNFα VHH is a bivalent antibody.