发明名称 |
METHODS AND COMPOSITIONS FOR APPLYING MOXIFLOXACIN TO THE EAR |
摘要 |
Methods and materials useful for applying moxifloxacin to the ear are described. The methods involve delivering a composition that contains at least one viscogenic agent and moxifloxacin or a salt thereof to the epidermal surface of the tympanic membrane via the ear canal. The composition is delivered to the tympanic membrane in a flowable form and, after delivery to the tympanic membrane, becomes sufficiently viscous such that the moxifloxacin is localized against the tympanic membrane. Such compositions can be used to prophylactically and/or therapeutically treat middle and inner ear conditions, including otitis media. |
申请公布号 |
EP2521547(A4) |
申请公布日期 |
2014.03.26 |
申请号 |
EP20110732210 |
申请日期 |
2011.01.07 |
申请人 |
REGENTS OF THE UNIVERSITY OF MINNESOTA;NOVARTIS AG |
发明人 |
SAWCHUK, RONALD J.;CHEUNG, BELINDA W.Y.;WALL, G. MICHAEL |
分类号 |
A61K9/06;A61K31/437;A61K47/10;A61K47/30;A61K47/36;A61K47/38;A61P27/16 |
主分类号 |
A61K9/06 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|