| 摘要 |
Disclosed are modulators of the human relaxin receptor 1, for example, of formula (I), wherein A, R1, and R2 are as defined herein, that are useful in treating mammalian relaxin receptor 1 mediated facets of human health, e.g., cardiovascular disease. Also disclosed is a composition comprising a pharmaceutically suitable carrier and at least one compound of the disclosure, and a method for therapeutic intervention in a facet of mammalian health that is mediated by a human relaxin receptor 1. |
| 申请人 |
THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES;THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES;MARUGAN, JUAN JOSE;XIAO, JINGBO;FERRER-ALEGRE, MARC;CHEN, CATHERINE;SOUTHALL, NOEL;ZHENG, WEI;AGOULNIK, ALEXANDER;AGOULNIK, IRINA |
发明人 |
MARUGAN, JUAN JOSE;XIAO, JINGBO;FERRER-ALEGRE, MARC;CHEN, CATHERINE;SOUTHALL, NOEL;ZHENG, WEI;AGOULNIK, ALEXANDER;AGOULNIK, IRINA |
