发明名称 |
TRIAZOLOTHIENOPYRIMIDINE COMPOUND INHIBITORS OF UREA TRANSPORTERS AND METHODS OF USING INHIBITORS |
摘要 |
<p>Provided herein are small molecule triazolothienopyrimidine compounds that inhibit urea transport activity of solute transporters, particularly the UT-B transporter. The compounds described herein are useful for increasing solute clearance in states of fluid overload and for treating refractory edema associated with cardiovascular, renal, and metabolic diseases, disorders, and conditions.</p> |
申请公布号 |
WO2013148813(A1) |
申请公布日期 |
2013.10.03 |
申请号 |
WO2013US34063 |
申请日期 |
2013.03.27 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA;ANDERSON, MARC |
发明人 |
ANDERSON, MARC;VERKMAN, ALAN, S. |
分类号 |
A61K31/519 |
主分类号 |
A61K31/519 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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