COMPOSITIONS AND METHODS FOR TREATING CHARCOT-MARIE-TOOTH DISEASES AND RELATED NEURONAL DISEASES

摘要

Provided are compositions and methods for the treatment of mutant glycyl-tRNA synthetase (GlyRS)-associated diseases, such as Charcot-Marie-Tooth (CMT) diseases, and related compositions and methods for diagnostic, drug discovery, and research applications. Also provided are mutant glycyl-tRNA synthetases and uses thereof.