| 摘要 |
Disclosed herein are 5-substituted quinazolinone derivatives of formula (II), wherein the substituents are as defined within the specification, processes for their preparation, compositions comprising said compounds and uses thereof. Said compounds are useful for treating, managing or preventing a disease or disorder, wherein the disease or disorder is cancer, a disorder associated with angiogenesis, pain, macular degeneration or related syndrome, a skin disease, a pulmonary disorder, an asbestos-related disorder, a parasitic disease, an immunodeficiency disorder, a CNS disorder, CNS injury, atherosclerosis or related disorder, dysfunctional sleep or a related disorder, hemoglobinopathy or a related disorder, or a TNFá related disorder. |
