发明名称 |
Monoclonal antibodies against claudin-18 for treatment of cancer |
摘要 |
The present invention provides antibodies useful as therapeutics for treating and/or preventing diseases associated with cells expressing CLD18, including tumor-related diseases such as gastric cancer, esophageal cancer, pancreatic cancer, lung cancer, ovarian cancer, colon cancer, hepatic cancer, head-neck cancer, and cancer of the gallbladder. |
申请公布号 |
EP2311879(A2) |
申请公布日期 |
2011.04.20 |
申请号 |
EP20100011776 |
申请日期 |
2006.11.24 |
申请人 |
GANYMED PHARMACEUTICALS AG;JOHANNES GUTENBERG-UNIVERSITAET MAINZ, VERTRETEN DURCH DEN PRAESIDENTEN |
发明人 |
SAHIN, UGUR;TUERECI, OEZLEM;USENER, DIRK;FRITZ, STEFAN;UHEREK, CHRISTOPH;BRANDENBURG, GUNDA;GEPPERT, HARALD-GERHARD;SCHROEDER, ANJA KRISTINA;THIEL, PHILIPPE |
分类号 |
C07K16/28;A61K39/00;A61K39/395;A61K45/06;A61K47/48;A61K51/10;A61P35/00;C07K16/18;C07K16/30;C12N5/12 |
主分类号 |
C07K16/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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