1-acyl-5-phenyl-1h-1, 5-benzodiazepine -2, 4-(3h, 5h)-diones prodn - - useful as psychosedatives, muscle relaxants and anticonvulsants

摘要

Title cpds. of formula (I): where R' = H, (1-15C) alkyl, halomethyl, cyclohexyl, Ph opt subst. by one or two hal, Me, MeO, or NO2, PhCH2, styryl, or a five membered O or S heterocyclic, R2 = H, hal, CF3 or NO2, and R3 = hal or CF3, are prepd. by a single step acylation of the corresp. N'-acyl, N2-acyl, o-phenylenediamine with a malonic acid dihalide.