Nukleotidsekvenser der koder for deregulerede phosphoglycerat-dehydrogenaser i coryneforme bakterier, samt fremgangsmåde til fremstilling af L-serin

摘要

The invention relates to nucleotide sequences of coryneform bacteria that encode proteins that are involved in the biosynthesis of L-serine and to a method for producing L-serine. According to the invention, at least 79 amino acids at the C terminus of the wild-type serA sequence are deleted, thereby producing a 3-phosphoglycerate dehydrogenase having a reduced feedback inhibition by L-serine vis-à-vis the wild-type sequence.