发明名称 HUMAN GM-CSF ANTIGEN BINDING PROTEINS.
摘要 <p>Antigen binding proteins that bind to human GM-CSF protein are provided. Nucleic acids encoding the antigen binding protein, vectors, and cells encoding the same are also provided. The antigen binding proteins can inhibit binding of GM-CSF to GM-CSFR, inhibit GM-CSF-induced proliferation and signaling of myeloid lineage cell lines and inhibit GM-CSF-induced activation of human monocytes.</p>
申请公布号 MX2010002968(A) 申请公布日期 2010.06.15
申请号 MX20100002968 申请日期 2008.09.18
申请人 AMGEN INC. 发明人 JACQUELINE A. KIRCHNER;KENNETH A. BRASEL;KARA OLSON;JOSE CARLOS ESCOBAR;DAUPHINE BARONE
分类号 C07K16/24;A61K39/395;C12N15/13 主分类号 C07K16/24
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