Makers for the diagnosis of susceptibility to lung cancer using HER-2 gene and method for predicting and analyzing susceptibility to lung cancer using the same

摘要

PURPOSE: A marker for diagnosing lung cancer susceptibility using HER-2 gene is provided to predict and screen high risk group of lung cancer, diagnose and treat lung cancer. CONSTITUTION: A marker for diagnosing lung cancer susceptibility comprises one or more polynucleotide selected from a group comprising: a polynucleotide having 1316th base of polynucleotide sequence number 1 (-3444th from translation initiator element of HER-2 gene) which C is substituted with T and comprising 100-500 serial DNA fragments, a polynucleotide having 2771th base which G is substituted with T and comprising 100-500 serial DNA fragments; and a polynucleotide having 32301th base which C is substituted with G and comprising 100-500 serial DNA fragments and its complementary polynucleotide.