发明名称 |
CORRECTION METHOD OF FUNCTIONAL ORGANISM'S DEFECTS CAUSED BY DAMAGED NERVE CELLS OF BRAIN |
摘要 |
FIELD: medicine. ^ SUBSTANCE: invention refers to medicine and namely to neurology and can be used for correction of damaged nerve cells of the brain, which was caused by means of mitochondrial toxin of 3-nitropropionic acid. Method is implemented in the following way: stereotactic transplantation of multipotent mesenchymal stromal cells (MMSC) of human adipose tissue which is pre-incubated in the medium containing 10 mcM of retinoic acid is performed during 6 days. ^ EFFECT: invention allows normalising pathologic changes of brain tissue and the associated neurological deficiency owing to transplantation of pre-incubated MMSC. ^ 1 tbl |
申请公布号 |
RU2368378(C1) |
申请公布日期 |
2009.09.27 |
申请号 |
RU20070148152 |
申请日期 |
2007.12.26 |
申请人 |
GOSUDARSTVENNOE UCHREZHDENIE NAUCHNYJ TSENTR NEVROLOGII ROSSIJSKOJ AKADEMII MEDITSINSKIKH NAUK |
发明人 |
BOLDYREV ALEKSANDR ALEKSANDROVICH;STEPANOVA MARIJA SERGEEVNA;STVOLINSKIJ SERGEJ L'VOVICH;RZHANINOVA ALLA ANATOL'EVNA;GOL'DSHTEJN DMITRIJ VADIMOVICH;KULIKOV ANDREJ VALENTINOVICH |
分类号 |
A61K31/19;A61K31/203;A61K35/12;A61P25/00 |
主分类号 |
A61K31/19 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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