发明名称 CORRECTION METHOD OF FUNCTIONAL ORGANISM'S DEFECTS CAUSED BY DAMAGED NERVE CELLS OF BRAIN
摘要 FIELD: medicine. ^ SUBSTANCE: invention refers to medicine and namely to neurology and can be used for correction of damaged nerve cells of the brain, which was caused by means of mitochondrial toxin of 3-nitropropionic acid. Method is implemented in the following way: stereotactic transplantation of multipotent mesenchymal stromal cells (MMSC) of human adipose tissue which is pre-incubated in the medium containing 10 mcM of retinoic acid is performed during 6 days. ^ EFFECT: invention allows normalising pathologic changes of brain tissue and the associated neurological deficiency owing to transplantation of pre-incubated MMSC. ^ 1 tbl
申请公布号 RU2368378(C1) 申请公布日期 2009.09.27
申请号 RU20070148152 申请日期 2007.12.26
申请人 GOSUDARSTVENNOE UCHREZHDENIE NAUCHNYJ TSENTR NEVROLOGII ROSSIJSKOJ AKADEMII MEDITSINSKIKH NAUK 发明人 BOLDYREV ALEKSANDR ALEKSANDROVICH;STEPANOVA MARIJA SERGEEVNA;STVOLINSKIJ SERGEJ L'VOVICH;RZHANINOVA ALLA ANATOL'EVNA;GOL'DSHTEJN DMITRIJ VADIMOVICH;KULIKOV ANDREJ VALENTINOVICH
分类号 A61K31/19;A61K31/203;A61K35/12;A61P25/00 主分类号 A61K31/19
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