The present invention relates to synthetic leader peptide sequences wherein N-linked glycasylation is lacking. The leader peptide (LP) is used in a DNA construct encoding a polypeptide having the structure: SP-LP-(DS)-(S)-(PS)-*gene*. The construct may be used in yeast.
申请公布号
WO9832867(A1)
申请公布日期
1998.07.30
申请号
WO1998DK00026
申请日期
1998.01.22
申请人
NOVO NORDISK A/S;KJELDSEN, THOMAS, BOERGLUM;HAVELUND, SVEND;PETTERSSON, ANNETTE, FROST;BALSCHMIDT, PER
发明人
KJELDSEN, THOMAS, BOERGLUM;HAVELUND, SVEND;PETTERSSON, ANNETTE, FROST;BALSCHMIDT, PER
