发明名称 |
COMPOSITIONS AND METHODS FOR ALTERING ELASTOGENESIS |
摘要 |
<p>Compositions and methods are provided for promoting elastin fiber formation (elastogenesis) in a cell, including methods that comprise contacting a cell that is capable of elastogenesis with (i) a mutated biglycan polypeptide that lacks chondrotin sulphate proteoglycan chains, (ii) a versican V3 isoform polypeptide that lacks most or all of the polypeptide regions encoded by one or more of exons 4, 5 or 6 or by exons 9-10 or 11-13, and/or with (iii) metastatin.</p> |
申请公布号 |
WO2008100789(A2) |
申请公布日期 |
2008.08.21 |
申请号 |
WO2008US53341 |
申请日期 |
2008.02.07 |
申请人 |
BENAROYA RESEARCH INSTITUTE AT VIRGINIA MASON;WIGHT, THOMAS, N.;MERRILESS, MERVYN |
发明人 |
WIGHT, THOMAS, N.;MERRILESS, MERVYN |
分类号 |
C12N15/06 |
主分类号 |
C12N15/06 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|