FIBRIN GLUE APPLICATOR SYSTEM

摘要

A fibrin glue applicator system is provided for dispensing a first and a second protein solution which form a biological adhesive when intermixed on an application site. The fibrin glue applicator system includes a coupler interface, a disposable loading unit (DLU), and a housing having a handle portion which includes a trigger operatively associated with a slide bar for dispensing the solutions from the DLU. Each piercer is in fluid communication with one of two cylinders of the DLU via a respective conduit connected to a respective main conduit. A first one-way valve is included within each conduit to open and close a path leading from the piercer to the main conduit. The first one-way valves are forced open by air pressure created when the loading lever connected to two pistons of the DLU is translated proximally causing the protein solutions to be transferred to their corresponding cylinder. The DLU is then mounted to the housing. The solutions are dispensed via two dispensing orifices each in fluid communication with one of the main conduits. A second one-way valve is fixed within each main conduit in proximity to each dispensing orifice to open and close a path leading from each cylinder to its corresponding dispensing orifice. The second one-way valves open when the solutions are forcibly transferred from the cylinders to the main conduits by depressing the trigger for dispensing the solutions from the two dispensing orifices. The first and second protein solutions are preferably fibrinogen and thrombin solutions which intermix on the application site to form a fibrin sealant.