发明名称 THERAPEUTIC AGENT FOR INTERSTITIAL PNEUMONIA
摘要 <p>Disclosed is a therapeutic agent for interstitial pneumonia, which ensures to exert the effect of superoxide dismutase (SOD) contained therein. Specifically disclosed is a therapeutic agent for interstitial pneumonia, which comprises 10 to 100 mg of lecithin-conjugated superoxide dismutase represented by the general formula (I), which further comprises sucrose for the purpose of increasing its stability, and which has a dosage form suitable for intravenous administration. SOD'(Q-B)&lt;SUB&gt;m&lt;/SUB&gt; (I) wherein SOD' represents a residue of superoxide dismutase; Q represents a chemical crosslink; B represents a residue produced by removing a hydrogen atom from a hydroxy group in lysolecithin which has the hydroxy group at position-2 of a glycerol moiety therein; and m represents an average number of lysolecithin molecules bound to one superoxide dismutase molecule and is an integer of 1 or greater.</p>
申请公布号 WO2008075706(A1) 申请公布日期 2008.06.26
申请号 WO2007JP74400 申请日期 2007.12.19
申请人 LTT BIO-PHARMA CO., LTD.;SHIRAI, KOUJI;KAWASHIMA, TATSUO;KURODA, TOSHIHISA;MIZUSHIMA, YUTAKA;MURAKAMI, MASAHIRO;FUKUZAKI, TOMOHARU 发明人 SHIRAI, KOUJI;KAWASHIMA, TATSUO;KURODA, TOSHIHISA;MIZUSHIMA, YUTAKA;MURAKAMI, MASAHIRO;FUKUZAKI, TOMOHARU
分类号 A61K38/45;A61K9/08;A61K31/573;A61K45/00;A61K47/24;A61K47/48;A61P11/00;A61P29/00 主分类号 A61K38/45
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