| 发明名称 |
POLYMER CONJUGATES OF NEUBLASTIN AND METHODS OF USING SAME |
| 摘要 |
A neublastin polypeptide suitable for formation of a conjugate comprising the neublastin polypeptide coupled to a polymer containing a polyalkylene glycol moiety is disclosed. The present conjugate has prolonged bioavailability relative to non-modified or wild-type forms of neublastin. The conjugates of the invention are usefully employed in therapeutic as well as diagnostic, applications. |
| 申请公布号 |
UA82983(C2) |
申请公布日期 |
2008.06.10 |
| 申请号 |
UA20030088104 |
申请日期 |
2002.01.25 |
| 申请人 |
BIOGEN IDEC MA INC. |
发明人 |
SAH DINAH W. Y.;PEPINSKY R. BLAKE;BORJACK-SJODIN PAULA ANN;MILLER STEPHAN S.;ROSSOMANDO ANTHONY |
| 分类号 |
C07K14/475;C12N15/09;A61K38/00;A61K39/00;A61K47/48;A61P3/10;A61P9/10;A61P13/12;A61P21/00;A61P25/00;A61P25/02;A61P25/04;A61P25/14;A61P25/16;A61P25/28;A61P29/02;A61P35/00;C07K14/00;C07K14/765;C07K19/00;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/12;C12P21/02 |
主分类号 |
C07K14/475 |
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