| 摘要 |
Disclosed herein is a method for treating an androgen-stimulated disease in a subject in need thereof by administering to the subject a composition containing an effective amount of an inhibitor of IkappaB kinase subunit alpha activity. The composition can also be administered to a subject at high risk for prostate cancer as a method for reducing the subject's risk thereof. A further method relates to identifying a modulator of transcriptional activity regulated by IkappaB kinase subunit alpha. Still another method relates to determining the IkappaB kinase subunit alpha-regulated transcriptional activity regulated by in a non-human mammalian test subject.
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