1H-BENZIMIDAZOLE-4-CARBOXAMIDES SUBSTITUTED WITH A QUATERNARY CARBON AT THE 2-POSITION ARE POTENT PARP INHIBITORS
摘要
Compounds of Formula (I) (I) inhibit the PARP enzyme and are useful for treating a disease or a disorder associated with PARP. Also disclosed are pharmaceutical compositions comprising compounds of Formula (I), methods of treatment comprising compounds of Formula (I), and methods of inhibiting the PARP enzyme comprising compounds of Formula (I).
申请公布号
WO2006110816(A3)
申请公布日期
2007.01.04
申请号
WO2006US13652
申请日期
2006.04.11
申请人
ABBOTT LABORATORIES;ZHU, GUIDONG;GONG, JIANCHUN;GANDHI, VIRAJKUMAR, B.;PENNING, THOMAS, D.;GIRANDA, VINCENT
发明人
ZHU, GUIDONG;GONG, JIANCHUN;GANDHI, VIRAJKUMAR, B.;PENNING, THOMAS, D.;GIRANDA, VINCENT