ATTENUATED SALMONELLA TYPHIMURIUM HAVING THERAPEUTIC EFFECTS ON ATOPIC DERMATITIS

摘要

A composition comprising attenuated Salmonella typhimurium is provided to increase the expression of interferon-gamma, lower the expression of IL-4 and inhibit the expression of IgE by inducing cytokine change in the body, thereby being effectively used for treating and preventing atopic dermatitis. The therapeutic composition for atopic dermatitis comprises attenuated Salmonella typhimurium as an effective ingredient. In the composition, the attenuated Salmonella typhimurium is an attenuated vaccine for preventing typhoid or Salmonella typhimurium BRD509.