发明名称 |
Stabilization of solid thyroid drug formulations |
摘要 |
Pharmaceutical formulations and dosage forms are provided having improved stability to moisture-induced degradation when compared with conventional dosage forms, especially tablets. The invention features low compression forms of thyroid drugs together with excipients, preferably in encapsulated forms. In other embodiments, relatively non-volatile oils can be admixed with the drug and/or the excipients to stabilize the formulation toward moisture-induced degradation. Hydrophobic powders are also optionally added to the formulations.
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申请公布号 |
US6855333(B1) |
申请公布日期 |
2005.02.15 |
申请号 |
US20000690973 |
申请日期 |
2000.10.18 |
申请人 |
MUTUAL PHARMACEUTICAL CO., INC. |
发明人 |
SPIREAS SPIRIDON |
分类号 |
A61K9/20;A61K9/48;A61K31/198;(IPC1-7):A61K9/48 |
主分类号 |
A61K9/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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