METHODS AND COMPOSITIONS FOR VACCINATION COMPRISING NUCLEIC ACID AND/OR POLYPEPTIDE SEQUENCES OF THE GENUS BORRELIA
摘要
The invention relates to antigens and nucleic acids encoding such antigens obtainable by screening a Borrelia genome, in particular an B. burgdorferi genome. In more specific aspects, the invention relates to methods of isolating such antigens and nucleic acids and to methods of using such isolated antigens for producing immune responses. The ability of an antigen to produce an immune response may be employed in vaccination or antibody preparation techniques.
申请公布号
WO2004103269(A2)
申请公布日期
2004.12.02
申请号
WO2003US33056
申请日期
2003.10.17
申请人
MACROGENICS, INC.;BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM;SYKES, KATHRYN, F.;HALE, KATHERINE, S.;JOHNSTON, STEPHEN, A.
发明人
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM;SYKES, KATHRYN, F.;HALE, KATHERINE, S.;JOHNSTON, STEPHEN, A.