| 发明名称 |
OPEN CHAIN PROLYL UREA-RELATED MODULATORS OF ANDROGEN RECEPTOR FUNCTION |
| 摘要 |
The invention provides for a pharmaceutical composition capable of modulating the androgen receptor comprising a compound of formula (I), wherein R1, R2, R3, X, Y, Z and G are as described herein. Further provided are methods of using such compounds for the treatment of nuclear hormone receptor-associated conditions, such as age related diseases, for example sarcopenia, and also provided are pharmaceutical compositions containing such compounds. |
| 申请公布号 |
WO2004045518(A2) |
申请公布日期 |
2004.06.03 |
| 申请号 |
WO2003US36331 |
申请日期 |
2003.11.13 |
| 申请人 |
BRISTOL-MYERS SQUIBB COMPANY;HAMANN, LAWRENCE, G.;AUGERI, DAVID, J.;MANFREDI, MARK, C. |
发明人 |
HAMANN, LAWRENCE, G.;AUGERI, DAVID, J.;MANFREDI, MARK, C. |
| 分类号 |
A61K31/401;A61K31/4025;A61K31/445;A61K31/454;A61K31/55;A61P3/04;A61P3/10;A61P9/12;A61P25/22;A61P25/24;C07D207/16;C07D211/06;C07D401/12 |
主分类号 |
A61K31/401 |
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