发明名称 Sulfoxide and bis-sulfoxide compounds and compositions for cholesterol management and related uses
摘要 The present invention relates to novel sulfoxide and bis-sulfoxide compounds, compositions comprising sulfoxide and bis-sulfoxide compounds, and methods useful for treating and preventing cardiovascular diseases, dyslipidemias, dysproteinemias, and glucose metabolism disorders comprising administering a composition comprising an ether compound. The compounds, compositions, and methods of the invention are also useful for treating and preventing Alzheimer's Disease, Syndrome X, peroxisome proliferator activated receptor-related disorders, septicemia, thrombotic disorders, obesity, pancreatitis, hypertension, renal disease, cancer, inflammation, and impotence. In certain embodiments, the compounds, compositions, and methods of the invention are useful in combination therapy with other therapeutics, such as hypocholesterolemic and hypoglycemic agents.
申请公布号 US6673780(B2) 申请公布日期 2004.01.06
申请号 US20010976899 申请日期 2001.10.11
申请人 ESPERION THERAPEUTICS, INC. 发明人 DASSEUX JEAN-LOUIS HENRI;ONICIU CARMEN DANIELA
分类号 A61P1/18;A61K31/10;A61P3/00;A61P3/04;A61P3/06;A61P3/08;A61P7/02;A61P9/00;A61P9/12;A61P13/12;A61P15/10;A61P25/28;A61P29/00;A61P31/04;A61P35/00;C07C59/347;C07C317/04;C07C317/10;C07C317/14;C07C317/18;C07C317/22;C07C317/24;C07C317/44;C07C323/60;C07D233/76;C07D233/86;C07D257/04;C07D261/12;C07D305/12;C07D307/32;C07D307/33;C07D309/12;C07D309/30;C07D309/38;C07D333/48;C07D335/02;C07F9/09;C07F9/24;C07F9/44;(IPC1-7):C02D498/12;A61K31/43 主分类号 A61P1/18
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