发明名称 THE USE OF SUBSTITUTED CYANOPYRROLIDINES AND COMBINATION PREPARATIONS CONTAINING THEM FOR TREATING HYPERLIPIDEMIA AND ASSOCIATED DISEASES
摘要 Disclosed are methods and compositions for the treatment of hyperlipidemia a nd conditions associated therewith, such as CHD, ischemic stroke, restenosis after angioplasty, peripheral vascular disease, intermittent claudication, myocardial infarction (e.g. necrosis and apoptosis), dyslipidemia and post- prandial lipemia. The methods include administration of a therapeutically effective amount of a compound of formula (I), wherein R is substituted adamantyl; and N is 0 to 3; in free form or in acid addition salt form, and a pharmaceutically acceptable carrier.
申请公布号 CA2487297(A1) 申请公布日期 2003.12.11
申请号 CA20032487297 申请日期 2003.06.02
申请人 NOVARTIS AG 发明人 HUGHES, THOMAS EDWARD;HOLMES, DAVID GRENVILLE
分类号 C07D207/16;A61K31/015;A61K31/05;A61K31/20;A61K31/22;A61K31/355;A61K31/366;A61K31/375;A61K31/40;A61K31/401;A61K31/405;A61K31/4415;A61K31/455;A61K31/616;A61K31/714;A61K45/00;A61K45/06;A61P3/06;A61P9/10;(IPC1-7):A61K31/40 主分类号 C07D207/16
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