发明名称 MEDICAMENT OBTAINED BY TOGETHER FUSING HOLLOW NANO- PARTICLE FORMING PROTEIN WITH CELL-TRANSDUCING SUBSTANCE FOR TREATING DISEASE
摘要 <P>PROBLEM TO BE SOLVED: To obtain a medicament for treating diseases, obtained by using protein hollow nano-particles, specifically acting on target cells or tissue, and capable of efficiently containing a protein medicine in the insides of the particles, and to provide a method for treating the diseases by using the medicament. <P>SOLUTION: The hollow nano-particles comprise a protein which has recognition ability of a specified cell, such as a hepatic cell, and particle-forming ability, wherein the protein is together fused with a cell-transducing substance for treating the diseases. A hepatitis B virus surface antigen protein is preferably used as the protein. An interferon or a hepatic cell growth factor is preferably used as the cell-transducing substance. <P>COPYRIGHT: (C)2004,JPO
申请公布号 JP2003286189(A) 申请公布日期 2003.10.07
申请号 JP20020097280 申请日期 2002.03.29
申请人 JAPAN SCIENCE & TECHNOLOGY CORP 发明人 KURODA SHUNICHI;TANIZAWA KATSUYUKI;KONDO AKIHIKO;UEDA MASAKAZU;SENOO SHOJI;TADA HIROKO
分类号 C12N15/09;A61K9/50;A61K35/12;A61K35/64;A61K35/76;A61K36/06;A61K38/00;A61K38/21;A61K38/22;A61K39/29;A61K48/00;A61P1/16;A61P35/00;C07K14/02 主分类号 C12N15/09
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