| 发明名称 |
THROMBIN INHIBITORS |
| 摘要 |
This invention relates to novel polyfluorinated alkyl derivatives of certain tripeptides, to the methods for their preparation, the intermediates therefore, to their use in inhibiting thrombin and lung tryptase and in their end-use application as anti-coagulants useful in treating thrombo- phlebitis and coronary thrombosis and in the treatment of asthma.
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| 申请公布号 |
CA2070254(C) |
申请公布日期 |
2003.08.19 |
| 申请号 |
CA19922070254 |
申请日期 |
1992.06.02 |
| 申请人 |
MERRELL DOW PHARMACEUTICALS INC. |
发明人 |
NEISES, BERNHARD;GANZHORN, AXEL;TARNUS, CELINE;BROERSMA, ROBERT J., JR. |
| 分类号 |
A61K38/00;A61K38/06;A61P7/02;A61P11/00;A61P43/00;C07K1/02;C07K1/113;C07K5/06;C07K5/08;C07K5/087;(IPC1-7):C07K5/08 |
主分类号 |
A61K38/00 |
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