发明名称 |
ASSAY FOR THE DETECTION OF FACTORS THAT MODULATE THE EXPRESSION OF INGAP |
摘要 |
A reporter construct contains mammalian INGAP 5'-regulatory region or a fragment thereof, a minimal promoter element from mammalian INGAP or a heterologous promoter, and a reporter gene. The reporter construct can be used to screen for agents which alone or in combination up-regulate or down- regulate reporter gene expression. Alternatively, the reporter construct can be used to screen for agents that bind to the hamster INGAP 5'-regulatory region or a fragment thereof.
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申请公布号 |
CA2470359(A1) |
申请公布日期 |
2003.07.24 |
申请号 |
CA20032470359 |
申请日期 |
2003.01.10 |
申请人 |
GMP ENDOTHERAPEUTICS, INC. |
发明人 |
VINIK, AARON I.;TAYLOR-FISHWICK, DAVID |
分类号 |
C12N15/09;A61K31/7088;A61K38/00;A61K45/00;A61K48/00;A61P3/04;A61P3/10;A61P5/50;C07K14/47;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12Q1/02;(IPC1-7):A61K38/24;C07K1/00;C07K14/00;C07K16/00;C07K17/00;C12N15/00;C12P21/06;A61K38/27;C12N15/63;C12Q1/68 |
主分类号 |
C12N15/09 |
代理机构 |
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