SUBSTITUTED ARYL-CYCLOALKANES, AND USE THEREOF AS ANTICANCER AGENTS

摘要

The invention concerns products of formula (I), wherein: A represents a saturated or partly saturated cyclic hydrocarbon, optionally substituted; X is selected from the group consisting of O, N-O(R2); Ar1 represents a substituted phenyl ring; and Ar2 is selected from the group consisting of certain substituted phenyl rings or nitrogenous heterocycles. Said products are useful as anticancer agents, in particular as tubulin polymerization inhibitors.